ADENOMAS INVOLVING THE EXTRAHEPATIC BILIARY TREE ARE RARE BUT HAVE AN AGGRESSIVE CLINICAL COURSE



Notes on the taxonomy of Rubus in southern Africa

The taxonomy of Rubus in South Africa is beset with problems.These include the introduction of extra-African species as ornamentals and crops, the apparent nike dunk high crimson tint segregation of new forms and finally hybridization with indigenous species.These problems are compounded by poor and incomplete collecting of Rubus in South Africa, a

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Neoantigen architectures define immunogenicity and drive immune evasion of tumors with heterogenous neoantigen expression

Background Intratumoral heterogeneity (ITH) and subclonal antigen expression blunt antitumor immunity and are associated with poor responses to immune-checkpoint blockade immunotherapy (ICB) in patients with cancer.The underlying mechanisms however thus far remained elusive, preventing the design of novel treatment approaches for patients with high

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